Uji Sensitivitas dan Spesitifitas Immuno Chromatography Test -Tuberculosis (ICT - TB) pada Penderita Tuberkulosis Paru di Kabupaten Bima-NTB

Abstract

Background: The problem of Tuberculosis (TB) is a healt problem that
has long been faced by various countries in the world, including
Indonesia. Tuberculosis is an infectious disease caused by infection
with the germ Mycobacterium tuberculosis. Tuberculosis disease mostly
affects the lung parenchyma (pulmonary TB). ICT-TB is a serological
test that is fast, simple and easy bto operate. The limited of number of
Genexpert MTB in Bima regency is an obstacle in establishing an early
tuberculosis.

Objective: To determinan the sensitivity and specificity of the immuno
chromatography test-tuberculosis (ICT-TB) method in TB patients.

Method: This study is an analytical abservational study, with a
purposive sampling approach, namely research samples taken from
serum specimens for the ICT-TB method and sputum for Genexpert
MTB as standart. The sensitivity and specificity for ICT-TB were
calculated manually using the Mc nemar formula in the 2 x 2 diagnostic
test table.

Results: The ICT- TB result showed 4 positive IgG respondents and 41
negative respondents, while the Genexpert MTB result showed 6 MTB
Detected and 39 MTB Not Detected. The ICT-TB sensitivity test result
for TCM were 50% and specificity 97,44%.

Conclusion: ICT-TB method has excellent specificity value. However ,
the ICT-TB method examination still has shortcomings that are not
found in the Genexpert MTB method.
Recommendation: Further research needs to be carried out using
samples of tuberculosis positive patients who have not received
treatment.