Antibacterial Effectiveness Test of Shallot Peel (Allium cepa L.) Against The Growth of Staphylococcus Aureus Bacteria

Abstract

Background: Escalating bacterial resistance to conventional antibiotics necessitates the exploration of botanical antibacterial agents. Red onion skin (Allium cepa L.) possesses bioactive constituents, including flavonoids, tannins, saponins, and polyphenols, with potential inhibitory effects against Staphylococcus aureus. Objective: This study evaluated the antibacterial efficacy of red onion skin decoction in suppressing the in vitro growth of S. aureus. Methods: An experimental laboratory design employing the well diffusion technique on Mueller-Hinton Agar (MHA) was utilized. Red onion skin decoction was applied at concentrations of , , and . Inhibition zones were quantified following a  incubation period at . Results: Decoction treatments at , , and  concentrations produced zero inhibition zones () against S. aureus. While the negative control exhibited no inhibitory activity, the positive control generated a marked inhibition zone of. Conclusion: Red onion skin decoction at tested concentrations (, , and ) demonstrates no antibacterial activity against S. aureus.